How do synaptic vesicles accumulate glutamate? – Kompass des Forschungsbereichs Information
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Description
Scientists from the Forschungszentrum Jülich from the Helmholtz Research Field Information and the University of South Florida have investigated and intricately modeled the processes in synaptic vesicles, a key component of neuron communication. Their findings could assist in developing therapeutic approaches for neurodegenerative diseases. (Source: Forschungszentrum Jülich – Press releases) In our brain, neurons communicate via neurotransmitters, which trigger electrical signals in downstream neurons by binding and activating specific receptors. Neurotransmitters are released through the fusion of synaptic vesicles, which contain large amounts of neurotransmitters. Scientists from the Institute of Molecular an Cellular Physiology of Forschungszentrum Jülich and the University…
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Synapses: Dividing communication, at the nanoscale
![How do synaptic vesicles accumulate glutamate? – Kompass des Forschungsbereichs Information](https://www.researchgate.net/publication/337697898/figure/fig2/AS:960140970840073@1605926854212/In-hippocampal-synapses-the-release-of-glutamate-depicted-as-dots-in-the-synaptic.png)
In hippocampal synapses, the release of glutamate (depicted as
![How do synaptic vesicles accumulate glutamate? – Kompass des Forschungsbereichs Information](https://ars.els-cdn.com/content/image/1-s2.0-S0896627312007209-gr3.jpg)
Kinetics of Synaptic Vesicle Refilling with Neurotransmitter
![How do synaptic vesicles accumulate glutamate? – Kompass des Forschungsbereichs Information](https://www.pnas.org/cms/10.1073/pnas.1604527113/asset/e71995a2-d0c6-47ac-935b-4967a28e7ee4/assets/graphic/pnas.1604527113sfig08.jpeg)
Unique pH dynamics in GABAergic synaptic vesicles illuminates the
![How do synaptic vesicles accumulate glutamate? – Kompass des Forschungsbereichs Information](https://www.researchgate.net/publication/338046708/figure/fig2/AS:837824723038211@1576764388152/Glutamate-synapse-Popoli-et-al-2012.jpg)
Glutamate synapse (Popoli et al., 2012).
![How do synaptic vesicles accumulate glutamate? – Kompass des Forschungsbereichs Information](https://ars.els-cdn.com/content/image/3-s2.0-B9780123749475000171-f17-04b-9780123749475.jpg)
Glutamatergic Synapse - an overview
![How do synaptic vesicles accumulate glutamate? – Kompass des Forschungsbereichs Information](https://blogs.helmholtz.de/research-field-information/wp-content/uploads/sites/30/2023/06/2IPC729-1-768x432.jpg)
Kompass des Forschungsbereichs Information – Page 5 – Kompass des
![How do synaptic vesicles accumulate glutamate? – Kompass des Forschungsbereichs Information](https://www.ncbi.nlm.nih.gov/books/NBK98204/bin/nadlerf1.jpg)
Figure 1, Diagrammatic representation of a glutamate synapse
![How do synaptic vesicles accumulate glutamate? – Kompass des Forschungsbereichs Information](https://media.springernature.com/m685/springer-static/image/art%3A10.1007%2Fs11064-016-2037-3/MediaObjects/11064_2016_2037_Fig4_HTML.gif)
Effective Mechanism for Synthesis of Neurotransmitter Glutamate
![How do synaptic vesicles accumulate glutamate? – Kompass des Forschungsbereichs Information](https://blogs.helmholtz.de/research-field-information/wp-content/uploads/sites/30/2023/02/cci_principle_press_release_2-1-768x283.png)
Technology Assessment: KIT advises the Bundestag for another five
![How do synaptic vesicles accumulate glutamate? – Kompass des Forschungsbereichs Information](https://www.researchgate.net/publication/277974353/figure/fig2/AS:1088177188155393@1636453067828/Synaptic-interaction-between-Zn-and-glutamate-system-observed-in-Alzheimers-disease.jpg)
Synaptic interaction between Zn²⁺ and glutamate system observed in
![How do synaptic vesicles accumulate glutamate? – Kompass des Forschungsbereichs Information](https://sanescohealth.com/wp-content/uploads/2016/06/Glutamate-Sanesco-Health.jpg)
Glutamate: The Primary Excitatory Neurotransmitter
![How do synaptic vesicles accumulate glutamate? – Kompass des Forschungsbereichs Information](https://blogs.helmholtz.de/research-field-information/wp-content/uploads/sites/30/2023/07/preview-2-2.jpg)
Kompass des Forschungsbereichs Information – Page 5 – Kompass des
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